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Polymer micelles as novel drug carrier: Adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer

✍ Scribed by Yokoyama Masayuki; Miyauchi Mizue; Yamada Noriko; Okano Teruo; Sakurai Yasuhisa; Kataoka Kazunori; Inoue Shohei

Book ID
119133938
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
714 KB
Volume
11
Category
Article
ISSN
0168-3659

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## Abstract PEG‐PLA copolymers with dumbbell‐ and Y‐shaped structures are prepared. They can self‐assemble from nanoparticles to micro‐sized fusiform micellar particles in aqueous solution. In particular the micelles formed by the (PLA)~2~‐PEG‐(PLA)~2~ particles show a better drug loading capacity