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Preparation and characterization of polymer micelles from poly(ethylene glycol)-poly(d,l-lactide) block copolymers as potential drug carrier

✍ Scribed by Kenji Yasugi; Yukio Nagasaki; Masao Kato; Kazunori Kataoka

Book ID
114163735
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
378 KB
Volume
62
Category
Article
ISSN
0168-3659

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## Abstract A novel type of biodegradable/biocompatible amphiphilic hyperbranched copolymer (H40‐PLA‐__b__‐MPEG) was synthesized. Its micellar properties were studied by DLS, fluorescence spectroscopy and TEM. The drug release profile showed that the H40‐PLA‐__b__‐MPEG micelles provide an initial b