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Folate-conjugated methoxy poly(ethylene glycol)/poly(ɛ-caprolactone) amphiphilic block copolymeric micelles for tumor-targeted drug delivery

✍ Scribed by Eun Kyoung Park; So Yeon Kim; Sang Bong Lee; Young Moo Lee


Book ID
113691084
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
240 KB
Volume
109
Category
Article
ISSN
0168-3659

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✍ Mani Prabaharan; Jamison J. Grailer; Douglas A. Steeber; Shaoqin Gong 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 427 KB

## Abstract Thermosensitive PNVCL‐__b__‐PEG block copolymer coupled with folic acid was prepared as an anti‐cancer drug carrier. This polymer self‐assembled into stable micelles in aqueous solutions at above 33 °C. At 37 °C, the release profile of PNVCL‐__b__‐PEG‐FA micelles showed a slower and mor