Folate-conjugated amphiphilic hyperbranched block copolymers based on Boltorn® H40, poly(l-lactide) and poly(ethylene glycol) for tumor-targeted drug delivery
✍ Scribed by Mani Prabaharan; Jamison J. Grailer; Srikanth Pilla; Douglas A. Steeber; Shaoqin Gong
- Book ID
- 108069995
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 596 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0142-9612
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Thermosensitive PNVCL‐__b__‐PEG block copolymer coupled with folic acid was prepared as an anti‐cancer drug carrier. This polymer self‐assembled into stable micelles in aqueous solutions at above 33 °C. At 37 °C, the release profile of PNVCL‐__b__‐PEG‐FA micelles showed a slower and mor
## Abstract A novel type of biodegradable/biocompatible amphiphilic hyperbranched copolymer (H40‐PLA‐__b__‐MPEG) was synthesized. Its micellar properties were studied by DLS, fluorescence spectroscopy and TEM. The drug release profile showed that the H40‐PLA‐__b__‐MPEG micelles provide an initial b