✦ LIBER ✦

Polymerase Chain Reaction Strategy

✍ Scribed by Arnheim, Norman; Erlich, Henry

Book ID: 118222272
Publisher: Annual Reviews
Year: 1992
Tongue: English
Weight: 782 KB
Volume: 61
Category: Article
ISSN: 0066-4154
DOI: 10.1146/annurev.bi.61.070192.001023

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A mathematical model for polymerase chain reaction (PCR) is developed, taking into account the three steps in this process: melting of DNA; primer annealing; and DNA synthesis (polymerization). Activity and deactivation of the polymerase enzyme as a function of temperature is incorporated in the kin