✦ LIBER ✦

The polymerase chain reaction

✍ Scribed by Jean M. DeMarchi

Book ID: 113294028
Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 431 KB
Volume: 12
Category: Article
ISSN: 0196-4399
DOI: 10.1016/0196-4399(90)90018-7

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A mathematical model for polymerase chain reaction (PCR) is developed, taking into account the three steps in this process: melting of DNA; primer annealing; and DNA synthesis (polymerization). Activity and deactivation of the polymerase enzyme as a function of temperature is incorporated in the kin