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Poly(ethylene glycol)-modified Nanocarriers for Tumor-targeted and Intracellular Delivery

✍ Scribed by Lilian E. van Vlerken; Tushar K. Vyas; Mansoor M. Amiji


Book ID
106493137
Publisher
Springer US
Year
2007
Tongue
English
Weight
347 KB
Volume
24
Category
Article
ISSN
0724-8741

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## Abstract Thermosensitive PNVCL‐__b__‐PEG block copolymer coupled with folic acid was prepared as an anti‐cancer drug carrier. This polymer self‐assembled into stable micelles in aqueous solutions at above 33 °C. At 37 °C, the release profile of PNVCL‐__b__‐PEG‐FA micelles showed a slower and mor