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cNGR conjugated poly(lactic acid)-poly(ethylene glycol) nanoparticles for targeted gene delivery

✍ Scribed by Chunxi Liu; Wangyang Yu; Zhijin Chen; Jian Zhang; Na Zhang


Book ID
113694772
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
580 KB
Volume
152
Category
Article
ISSN
0168-3659

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## Abstract In this study, a new poly(lactic acid)–poly (ethylene oxide)‐Arg‐Gly‐Asp (PLA‐PEO‐RGD) derivative was synthesized, and paclitaxel‐loaded PLA‐PEO‐RGD micelles were prepared by this derivative. The solubility assay showed that micelles mixed with Pluronic F‐68 as surfactant could increase