We have been interested for some time in the nucleophilic addition reactions to carl-6 bony1 compounds , the interpretation of our kinetic data has lead us to conclude that the position of the transition state along the reaction coordinate is not the same for all reactions and depends instead upon t
Pmo analysis of cycloadditions- II. The transition state of the addition of formonitrile oxide to acetylene
β Scribed by Reiner Sustmann; Willi Sicking
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 525 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4020
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π SIMILAR VOLUMES
We wish to report here the results of kinetic studies on the hydrochlorination of phenylallene 1 and its derivatives, and discuss about a salient characteristic of this reaction in its transition state.
The recently proposed (1) empirical -de1 ofasymetric induction vam baeed on the asamption that little bond breahiq and mahlng marha the dlastereaeric transition state8 that control product atereorpecificity. Thus, diantcreomeric product ratioa A/B were predicted with
As we haVe previously pointed out], the position of the Transition State along the reaction coordinate is a matter of controversy among workers in the field of nucleophilic addition reactions to carbonyl compounds. Some authors claim that the transition state is always "Reactant-like" whatever may b
Molecular mechanics calculations on model canpounds are used to evaluate the steric lnteractlons m acycllc aldol and related transition states. The develomnt of highly stereoselective aldol and related C-C bond-fonng reactions continues to be a dominant theme of synthetic organic chemistry.la In the
## Abstract An analysis of published human buccal absorption data of an acid and a base at six pH values extends multiβpH QSAR to an extreme: QSAR on a single compound. The compounds analyzed are 4β__n__βhexylphenylacetic acid and propranolol. This analysis might be considered as much an analysis o