✦ LIBER ✦
Concerning the relevance of ethane conformational analysis to acyclic aldol transition states
✍ Scribed by Dennis A. Dougherty
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 212 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Molecular mechanics calculations on model canpounds are used to evaluate the steric lnteractlons m acycllc aldol and related transition states. The develomnt of highly stereoselective aldol and related C-C bond-fonng reactions continues to be a dominant theme of synthetic organic chemistry.la In the presence of chelating counterlons, a six-membered cyclic transition state has proven to be a very useful model.lb Relevant sterlc lnteractlons and thus the more favorable transltlon states