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Platelet monoamine oxidase-B activity in Parkinson's disease

✍ Scribed by G. B. Steventon; S. G. Sturman; M. T. E. Heafield; R. H. Waring; J. Napier; A. C. Williams

Publisher
Springer
Year
1989
Tongue
English
Weight
425 KB
Volume
1
Category
Article
ISSN
1435-1463

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Monoamine oxidase B (MAO-B) is implicated in the cause of Parkinson's disease (PD) because of its role in metabolizing the neurotoxin l-methyl-4-phenyl-l,2,3,6-tetrahydropyridine, and forming H,02 during dopamine metabolism. Altered MAO-B activity has been observed in PD platelets. Polymerase chain