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Altered Platelet Monoamine Oxidase-B Activity in Idiopathic Parkinson’s Disease

✍ Scribed by Maroof Husain; Rakesh Shukla; Madhu Dikshit; Pradeep K. Maheshwari; Devika Nag; Rikhab C. Srimal; Prahlad K. Seth; Vinay K. Khanna

Publisher
Springer
Year
2009
Tongue
English
Weight
214 KB
Volume
34
Category
Article
ISSN
0364-3190

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✍ Janice H. Kurth; Dr. Matthias C. Kurth; Shirley E. Poduslo; John D. Schwankhaus 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 685 KB

Monoamine oxidase B (MAO-B) is implicated in the cause of Parkinson's disease (PD) because of its role in metabolizing the neurotoxin l-methyl-4-phenyl-l,2,3,6-tetrahydropyridine, and forming H,02 during dopamine metabolism. Altered MAO-B activity has been observed in PD platelets. Polymerase chain