An allelic association study of monoamine oxidase B in parkinson's disease
β Scribed by Dr. S. L. Ho; A. L. Kapadi; D. B. Ramsden; A. C. Williams
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 315 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0364-5134
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π SIMILAR VOLUMES
## Abstract Cigarette smoking is associated with reduced monoamine oxidase B (MAO B) activity. Polymorphisms of the __MAO B__ gene may modify the relationship between smoking and Parkinson's Disease (PD). We examined the association of MAO B intron 13 G/A polymorphism and risk of PD, and the modula
## Monoamine oxidase B (MAO -B ) is an enzyme that has relevance for Parkinson disease (PD) because of its roles in catabolizing dopamine and potentially activating exogenous neurotoxicants. A polymorphism of the gene encoding MAO-B has been identified as a single base change (A or G) in intron