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Platelet-derived growth factor Phorbol ester induces the expression of the B-chain but not of the A-chain in HEL cells

✍ Scribed by H.A. Weich; D. Herbst; H.U. Schairer; J. Hoppe


Book ID
115920045
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
824 KB
Volume
213
Category
Article
ISSN
0014-5793

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MBA-2, bone marrow-derived endothelial stromal cells, express platelet-derived growth factor (PDGF) A and B chain mRNAs and secrete PDCF activity that is induced by TGF-beta. Either chain of the PDGF molecule could modulate hematopoiesis and stromal cell growth. lntracellular pathways that regulate