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Thrombin-induced proliferation and expression of platelet-derived growth factor-A chain gene in human vascular smooth muscle cells

โœ Scribed by Chryso Kanthou; Graham Parry; Errol Wijelath; Vijay Vir Kakkar; Catherine Demoliou-Mason


Book ID
115926638
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
465 KB
Volume
314
Category
Article
ISSN
0014-5793

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Proliferation of smooth muscle cells from the pulmonary arteries and aortas of fetal calves is inhibited by heparin in vitro. This effect is reversible and dose dependent. Comparisons with effects of other polysaccharides indicate that only extensively sulfated polysaccharides inhibit proliferation