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Plasma 249Ser p53 mutation in patients with hepatocellular carcinoma residing in a high risk area

✍ Scribed by Lu Dong-Dong; Zhang Xi-Ran

Book ID
114778032
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2003
Tongue
English
Weight
645 KB
Volume
7
Category
Article
ISSN
1582-1838

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## Abstract Hepatocellular carcinoma (HCC) is frequent in areas of high exposure to aflatoxin and high prevalence of HBV infection, such as western Africa and south‐east China. A selective mutation in __TP53__ (AGGβ†’AGT at codon 249, Argβ†’Ser) has been identified as a hotspot in HCCs from such areas,