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Piperidine-mediated synthesis of thiazolyl chalcones and their derivatives as potent antimicrobial agents

โœ Scribed by Venkatesan, P.; Maruthavanan, T.


Book ID
125846916
Publisher
Taylor and Francis Group
Year
2012
Tongue
English
Weight
206 KB
Volume
26
Category
Article
ISSN
1478-6419

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Piperidine-mediated synthesis of thiazol
โœ P. Venkatesan; T. Maruthavanan ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 107 KB

## Abstract A series of new thiazolyl chalcones, 1โ€[2โ€aminoโ€4โ€methylโ€1, 3โ€thiazolโ€5โ€yl]โ€3โ€arylโ€propโ€2โ€enโ€1โ€one were prepared by piperidine mediated Claisenโ€Schmidt condensation of thiazolyl ketone with substituted aromatic aldehyde. These chalcones on cyclization gave 2โ€aminoโ€6โ€(2โ€aminoโ€4โ€methylโ€1,