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PIP3 pathway in regulatory T cells and autoimmunity

✍ Scribed by Masaki Kashiwada; Ping Lu; Paul B. Rothman


Book ID
107572322
Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
417 KB
Volume
39
Category
Article
ISSN
0257-277X

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## Abstract CD4^+^CD25^+^ regulatory T cells (Treg) appear to be critical in regulating immune responses to self‐antigens. Treg deficiency is associated with several human autoimmune diseases. Although substantial progress has been made in the study of murine and human Treg, their fundamental mecha