Regulatory T cells in experimental autoimmune disease
β Scribed by Suri-Payer, Elisabeth ;Fritzsching, Benedikt
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 299 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0344-4325
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The immune system is a delicately balanced network of interacting cells. In recent years, the concept of immune regulation/suppression has been firmly established, and both natural and induced regulatory cells play vital roles in protection from autoimmune disease. Recent work has revealed the diver
## Abstract CD4^+^CD25^+^ regulatory T cells (Treg) appear to be critical in regulating immune responses to selfβantigens. Treg deficiency is associated with several human autoimmune diseases. Although substantial progress has been made in the study of murine and human Treg, their fundamental mecha