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IPEX,FOXP3and regulatory T-cells: a model for autoimmunity

✍ Scribed by Hans D. Ochs; Eleonora Gambineri; Troy R. Torgerson


Book ID
107572270
Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
218 KB
Volume
38
Category
Article
ISSN
0257-277X

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## Abstract FOXP3 is a specific marker for naturally occurring regulatory T cells (nTreg). FOXP3 expression is correlated with development and function of nTreg. Recent evidence suggests that, upon activation, human effector T (Teff) cells and type 1 regulatory T (Tr1) cells can express FOXP3, albe