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Piecing together the family portrait of TCR-CD3 complexes

✍ Scribed by Kuhns, Michael S.; Badgandi, Hemant B.

Book ID
119829349
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
938 KB
Volume
250
Category
Article
ISSN
0105-2896

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πŸ“œ SIMILAR VOLUMES

Assembly of the TCR/CD3 complex: CD3Ο΅/Ξ΄
Assembly of the TCR/CD3 complex: CD3Ο΅/Ξ΄ and CD3Ο΅/Ξ³ dimers associate indistinctly with both TCRΞ± and TCRΞ² chains. Evidence for a double TCR heterodimer model
✍ Ester San JosΓ©; Almudena G. Sahuquillo; Rafael Bragado; Balbino AlarcΓ³n πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 188 KB

The TCR/CD3 complex is composed of six subunits which are expressed on the cell surface in a coordinate fashion after assembly in the endoplasmic reticulum (ER). The TCR/CD3 complex is assembled after a series of pairwise interactions involving the formation of dimers of CD3 epsilon with either CD3