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Genetic reconstitution of the T cell receptor (TcR) α/β heterodimer restores the association of CD3 ζ2 with the TcR/CD3 complex

✍ Scribed by Richard S. Blumberg; Jaime Sancho; Steven C. Ley; Francis V. McDermott; Kut-Nie Tan; James Breitmeyer; Cox Terhorst


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
981 KB
Volume
21
Category
Article
ISSN
0014-2980

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Assembly of the TCR/CD3 complex: CD3ϵ/δ
✍ Ester San José; Almudena G. Sahuquillo; Rafael Bragado; Balbino Alarcón 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB

The TCR/CD3 complex is composed of six subunits which are expressed on the cell surface in a coordinate fashion after assembly in the endoplasmic reticulum (ER). The TCR/CD3 complex is assembled after a series of pairwise interactions involving the formation of dimers of CD3 epsilon with either CD3