Evolution of T cell receptor (TCR) α β heterodimer assembly with the CD3 complex
✍ Scribed by Cécile Gouaillard; Anne Huchenq-Champagne; Jacques Arnaud; Chen-lo H. Chen; Bent Rubin
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 137 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0014-2980
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The TCR/CD3 complex is composed of six subunits which are expressed on the cell surface in a coordinate fashion after assembly in the endoplasmic reticulum (ER). The TCR/CD3 complex is assembled after a series of pairwise interactions involving the formation of dimers of CD3 epsilon with either CD3
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