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The T cell antigen receptor α and β chains interact via distinct regions with CD3 chains

✍ Scribed by Nicholas Manolios; Owen Kemp; Zhan Guo Li

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
1016 KB
Volume
24
Category
Article
ISSN
0014-2980

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Structural comparison of α/β and γ/δ T c
Structural comparison of α/β and γ/δ T cell receptor-CD3 complexes reveals identical subunit interactions but distinct cross-linking patterns of T cell receptor chains
✍ Joost van Neerven; John E. Coligan; Frits Koning 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 722 KB

## Abstract Here we compare the subunit interactions within the α/β and γ/δ T cell receptor‐CD3 (TcR‐CD3) complexes. By using different detergent solubilization protocols, subunit interactions can be defined within such cell surface receptor complexes. It was found that in both TcR‐CD3 complexes an