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Differential interaction of the CD2 extracellular and intracellular domains with the tyrosine phosphatase CD45 and the ζ chain of the TCR/CD3/ζ complex

✍ Scribed by Anne M. Verhagen; Burkhart Schraven; Martin Wild; Reinhard Wallich; Stefan C. Meuer


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
1022 KB
Volume
26
Category
Article
ISSN
0014-2980

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Assembly of the TCR/CD3 complex: CD3ϵ/δ
✍ Ester San José; Almudena G. Sahuquillo; Rafael Bragado; Balbino Alarcón 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB

The TCR/CD3 complex is composed of six subunits which are expressed on the cell surface in a coordinate fashion after assembly in the endoplasmic reticulum (ER). The TCR/CD3 complex is assembled after a series of pairwise interactions involving the formation of dimers of CD3 epsilon with either CD3