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Phthaloyl group : a new amino protecting group of deoxyadenosine in oligonucleotide synthesis

โœ Scribed by Akiko Kume; Mitsuo Sekine; Tsujiaki Hata


Publisher
Elsevier Science
Year
1982
Tongue
French
Weight
265 KB
Volume
23
Category
Article
ISSN
0040-4039

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4-Cyano-2-butenyl group: A new type of p
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4-Cyano-2-butenyl (CB) is a new type of protecting group for the intemucleotidic bonds in the synthesis of oligodeoxyribonucleotides by the phosphoramidite approach. This group is stable to acidic conditions and can be removed under mild conditions by a 8-elimination pathway using aqueous ammonium h