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Photooxygenation of 7,12-dimethylbenz(a)anthracene

✍ Scribed by Mahendra K. Logani; Willodene A. Austin; Ronald E. Davies


Book ID
104236050
Publisher
Elsevier Science
Year
1977
Tongue
French
Weight
194 KB
Volume
18
Category
Article
ISSN
0040-4039

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Photosensitivity of dna-bound 7,12-dimet
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## Abstract Structural information about the products formed when 7,12‐dimethylbenz(__a__)anthracene (DMBA) is bound to DNA in mammalian cell cultures has been sought through studies of the photosensitivities of these products and of various model compounds. Under conditions of light exposure in wh

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## Abstract One of the most potent carcinogens is 7,12‐dimethylbenz(a)anthracene (7,12‐DMBA), which is used routinely to conduct studies to evaluate carcinogen inhibitors. Its pharmacokinetics have not been reported in the literature. In view of its significant effects on drug metabolizing enzymes