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Identification of 8,9-dihydro-8,9-dihydroxy-7,12-dimethylbenz (a) anthracene as a rat liver metabolite of 7,12-dimethylbenz (a) anthracene

✍ Scribed by Charles E. Morreal; Vitauts Alks; Arthur J. Spiess

Book ID
115773015
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
287 KB
Volume
25
Category
Article
ISSN
0006-2952

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Disposition kinetics of 7,12-dimethylben
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✍ Dr Sarfaraz K. Niazi; Musarrat Hussain πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 345 KB πŸ‘ 1 views

## Abstract One of the most potent carcinogens is 7,12‐dimethylbenz(a)anthracene (7,12‐DMBA), which is used routinely to conduct studies to evaluate carcinogen inhibitors. Its pharmacokinetics have not been reported in the literature. In view of its significant effects on drug metabolizing enzymes