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Cell-specific metabolic activation of 7,12-dimethylbenz[a]anthracene in rat testis

✍ Scribed by Antonis Georgellis; Jan Rydström

Book ID
113137184
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
835 KB
Volume
72
Category
Article
ISSN
0009-2797

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Disposition kinetics of 7,12-dimethylben
Disposition kinetics of 7,12-dimethylbenz(a)anthracene in rats
✍ Dr Sarfaraz K. Niazi; Musarrat Hussain 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 345 KB 👁 1 views

## Abstract One of the most potent carcinogens is 7,12‐dimethylbenz(a)anthracene (7,12‐DMBA), which is used routinely to conduct studies to evaluate carcinogen inhibitors. Its pharmacokinetics have not been reported in the literature. In view of its significant effects on drug metabolizing enzymes