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Mechanisms of regulation of rat ovarian 7,12-dimethylbenz[a]anthracene hydroxylase

✍ Scribed by Margot Bengtsson; Yu Dong; Donald R. Mattison; Jan Rydstrom


Book ID
113137062
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
699 KB
Volume
63
Category
Article
ISSN
0009-2797

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## Abstract One of the most potent carcinogens is 7,12‐dimethylbenz(a)anthracene (7,12‐DMBA), which is used routinely to conduct studies to evaluate carcinogen inhibitors. Its pharmacokinetics have not been reported in the literature. In view of its significant effects on drug metabolizing enzymes