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Phenotype and function of human B cells expressing CD70 (CD27 ligand)

✍ Scribed by Susanne M. A. Lens; Rolien De Jong; Berend Hooibrink; Gerrit Koopman; Steven T. Pals; Marinus H. J. van Oers; René A. W. van Lier

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
754 KB
Volume
26
Category
Article
ISSN
0014-2980

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## Abstract CD70 (CD27 ligand) has been implicated in proapoptotic signals mediated by its receptor CD27 in lymphocytes as well as in proliferative effects induced by reverse signaling in CD70‐positive hematopoetic tumor cells. We were able to show that CD70 is expressed at the mRNA and protein lev