CD27/CD70 interaction directly drives B cell IgG and IgM synthesis
β Scribed by Kazunaga Agematsu; Tetsuji Kobata; Feng-Chun Yang; Takayuki Nakazawa; Keitaro Fukushima; Masashi Kitahara; Tetsuo Mori; Kanji Sugita; Chikao Morimoto; Atsushi Komiyama
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 505 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Objective Generalized DNA hypomethylation contributes to altered T cell function and gene expression in systemic lupus erythematosus (SLE). Some of the overexpressed genes participate in the disease process, but the full repertoire of genes affected is unknown. Methylationβsensitive
## Abstract We studied the ability of B lymphocytes from patients with Xβlinked hyper IgM syndrome (HIGM1) to be activated via the CD40 membrane receptor. HIGM1 is caused by a CD40 ligand gene mutation, leading to defective expression on the membrane of activated T lymphocytes. We found that trigge