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Phase II trial of echinomycin in advanced soft tissue sarcomas

✍ Scribed by Sarah A. Taylor; Barbara Metch; Stanley P. Balcerzak; Karl H. Hanson

Publisher
Springer US
Year
1990
Tongue
English
Weight
232 KB
Volume
8
Category
Article
ISSN
0167-6997

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✦ Synopsis

Thirty-four patients with advanced soft tissue sarcomas were entered in a phase II trial of echinomycin. Patients received 1.2 mg/m 2 intravenously (i.v.) weekly times four followed by a two week rest period. There were no objective responses. Dose limiting toxicity was gastrointestinal. Echinomycin given on this weekly schedule is inactive in treating previously treated patients with advanced soft tissue sarcomas.

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