A phase II trial of PALA+dipyridamole in patients with advanced soft-tissue sarcoma
β Scribed by Ephraim S. Casper; Jose Baselga; Tracy B. Smart; Gordon B. Magill; Maurie Markman; Alan Ranhosky
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 455 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0344-5704
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π SIMILAR VOLUMES
Thirty-six previously treated adult patients with advanced soft tissue sarcomas received CPDD 120 mg/m2 with mannitol diuresis. There were only two (6%) partial responses and five (15%) minor responses in 34 evaluable patients. Toxicity included nausea and vomiting, myelosuppression, mild ototoxicit
Thirty-four patients with advanced soft tissue sarcomas were entered in a phase II trial of echinomycin. Patients received 1.2 mg/m 2 intravenously (i.v.) weekly times four followed by a two week rest period. There were no objective responses. Dose limiting toxicity was gastrointestinal. Echinomycin