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A phase II clinical trial of echinomycin in metastatic soft tissue sarcoma

✍ Scribed by William J. Gradishar; Nicholas J. Vogelzang; Lary J. Kilton; Steven J. Leibach; Alfred W. Rademaker; Suzanne French; Al. B. Benson


Publisher
Springer US
Year
1995
Tongue
English
Weight
285 KB
Volume
13
Category
Article
ISSN
0167-6997

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Phase II trial of echinomycin in advance
✍ Sarah A. Taylor; Barbara Metch; Stanley P. Balcerzak; Karl H. Hanson πŸ“‚ Article πŸ“… 1990 πŸ› Springer US 🌐 English βš– 232 KB

Thirty-four patients with advanced soft tissue sarcomas were entered in a phase II trial of echinomycin. Patients received 1.2 mg/m 2 intravenously (i.v.) weekly times four followed by a two week rest period. There were no objective responses. Dose limiting toxicity was gastrointestinal. Echinomycin

A phase II trial of temozolomide in pati
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## Abstract ## BACKGROUND The objective of this study was to assess the efficacy and toxicity of the imidazotetrazine derivative temozolomide for patients with unresectable or metastatic soft tissue sarcoma. ## METHODS Twenty‐five of 26 patients were eligible and assessable for toxicity and resp