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Phase II study of 4′-iodo-4′-deoxydoxorubicin in patients with advanced, measurable non-small cell lung cancer


Book ID
122492990
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
148 KB
Volume
11
Category
Article
ISSN
0169-5002

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Phase II trial of esorubicin (4′deoxydox
✍ James R. Rigas; Mark G. Kris; Richard J. Gralla; Robert T. Heelan; Linda D. Mark 📂 Article 📅 1991 🏛 Springer US 🌐 English ⚖ 264 KB

Esorubicin (4'-deoxydoxorubicin or DxDx) is an analog of doxorubicin with preclinical antitumor activity and no significant cardiotoxicity in model systems. Eleven patients with small cell lung cancer who had previously received chemotherapy were given esorubicin (25 mg/m 2 intravenously) every 3 we