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A phase II study of 4-deoxydoxorubicin in advanced breast cancer

✍ Scribed by Knight, Robert K.; Rubens, Robert D.; Rankin, Elaine M.


Book ID
123080179
Publisher
Elsevier Science
Year
1987
Weight
732 KB
Volume
23
Category
Article
ISSN
0277-5379

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Idarubicin (4-demethoxydaunorubicin: DMDNR) is an orally active analogue of daunorubicin that has shown promising activity in animal and early clinical studies. We gave idarubicin in a phase II study to patients with advanced breast cancer unresponsive to hormonal manipulation and in some cases to s