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4′-O-Tetrahydropyranyl-doxorubicin in advanced breast cancer: a phase II study

✍ Scribed by Hellmut Samonigg; Anne-Katrin Kasparek; Herbert Stöger; Marianne Schmid; Bernd Eber; Gerhard Stark; Viktor Weinrauch; Karl Pfeiffer; Michael Smola; Peter Steindorfer; Peter Lechner

Publisher
Springer
Year
1990
Tongue
English
Weight
420 KB
Volume
26
Category
Article
ISSN
0344-5704

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Idarubicin (4-demethoxydaunorubicin: DMDNR) is an orally active analogue of daunorubicin that has shown promising activity in animal and early clinical studies. We gave idarubicin in a phase II study to patients with advanced breast cancer unresponsive to hormonal manipulation and in some cases to s