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Phase II studies of 4′-iodo-4′-deoxydoxorubicin in advanced non-small cell lung, colon and breast cancers


Book ID
122004774
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
157 KB
Volume
8
Category
Article
ISSN
0169-5002

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Phase II trial of esorubicin (4′deoxydox
✍ James R. Rigas; Mark G. Kris; Richard J. Gralla; Robert T. Heelan; Linda D. Mark 📂 Article 📅 1991 🏛 Springer US 🌐 English ⚖ 264 KB

Esorubicin (4'-deoxydoxorubicin or DxDx) is an analog of doxorubicin with preclinical antitumor activity and no significant cardiotoxicity in model systems. Eleven patients with small cell lung cancer who had previously received chemotherapy were given esorubicin (25 mg/m 2 intravenously) every 3 we