Phase II study of 4′-iodo-4′-deoxydoxorubicin in non-resectable non-small-cell lung cancer
✍ Scribed by Jens Benn Sørensen; Lars Stenbygaard; Lars Drivsholm; Per Dombernowsky; Heine H. Hansen
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 401 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0344-5704
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📜 SIMILAR VOLUMES
Esorubicin (4'-deoxydoxorubicin or DxDx) is an analog of doxorubicin with preclinical antitumor activity and no significant cardiotoxicity in model systems. Eleven patients with small cell lung cancer who had previously received chemotherapy were given esorubicin (25 mg/m 2 intravenously) every 3 we
A phase II trial of 4' Deoxydoxorubicin (DXDX) was conducted in unresectable previously untreated non-small cell lung cancer patients. DXDX was administered every 3 weeks by short intravenous infusion at a starting dose of 30 mg/m2, with dose escalation to 40 mg/m2 toxicity permitting. Four response