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Pharmacology and Pharmacokinetics || Comparative Pharmacokinetics of the Anticoagulant Effect of Coumarin Drugs in Man and Rat

โœ Scribed by Teorell, Torsten; Dedrick, Robert L.; Condliffe, Peter G.


Book ID
120427938
Publisher
Springer US
Year
1972
Weight
965 KB
Category
Article
ISBN
1468420550

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Comparative pharmacokinetics of coumarin
โœ Gerhard Levy; Donald E. Mager; Wing K. Cheung; William J. Jusko ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 142 KB

The anticoagulant warfarin exemplifies a type of drug that exhibits high affinity to pharmacologic target sites of limited capacity, resulting in unusual concentration-dependent distribution and elimination properties. The time course of warfarin concentrations in the serum, liver, kidneys, muscle,