Pharmacokinetics of aditoprim and trimet
โ
M. Perwaiz Iqbal; M. Khalid Ashfaq; Sarfaraz K. Niazi; M. Mahboobali; Khalid N.
๐
Article
๐
1994
๐
John Wiley and Sons
๐
English
โ 250 KB
๐ 1 views
Pharmacokinetic parameters of two antifolates, trimethoprim and aditoprim, were studied in buffalo calves. The elimination half-life of aditoprim (6-14 h) was nearly twice as long as that of trimethoprim (3.08h) and compares well with values observed in heifers. This longer half-life of aditoprim is