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Pharmacokinetics of Trimethoprim in Buffalo calves

โœ Scribed by Jain, S. K. ;Uppal, R. P.


Book ID
115158073
Publisher
Wiley (Blackwell Publishing)
Year
2010
Weight
332 KB
Volume
30
Category
Article
ISSN
0177-0543

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Pharmacokinetics of aditoprim and trimet
โœ M. Perwaiz Iqbal; M. Khalid Ashfaq; Sarfaraz K. Niazi; M. Mahboobali; Khalid N. ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 250 KB ๐Ÿ‘ 1 views

Pharmacokinetic parameters of two antifolates, trimethoprim and aditoprim, were studied in buffalo calves. The elimination half-life of aditoprim (6-14 h) was nearly twice as long as that of trimethoprim (3.08h) and compares well with values observed in heifers. This longer half-life of aditoprim is