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Pharmacokinetics and Urinary Excretion of Sulphadimidine in Buffalo Calves

โœ Scribed by Jain, S. K. ;Punia, J. S. ;Garg, B. D.


Book ID
114430179
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
96 KB
Volume
47
Category
Article
ISSN
0931-184X

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Pharmacokinetic parameters of two antifolates, trimethoprim and aditoprim, were studied in buffalo calves. The elimination half-life of aditoprim (6-14 h) was nearly twice as long as that of trimethoprim (3.08h) and compares well with values observed in heifers. This longer half-life of aditoprim is