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Pharmacokinetics of methysergide and its metabolite methylergometrine in man

✍ Scribed by U. Bredberg; G. S. Eyjolfsdottir; L. Paalzow; P. Tfelt-Hansen; V. Tfelt-Hansen

Publisher
Springer
Year
1986
Tongue
English
Weight
231 KB
Volume
30
Category
Article
ISSN
0031-6970

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After i.m. injection nicomorphine is relatively slowly absorbed from the muscular depot and is found in the serum for approximately 1 h. The rate of absorption differs between patients and governs the overall pharmacokinetic profile of the compound. The relative AUCs were nicomorphine 18%, 6-nicotin