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Pharmacokinetics of ketanserin and its metabolite ketanserin-ol in man after intravenous, intramuscular and oral administration

✍ Scribed by J. Heykants; A. Van Peer; R. Woestenborghs; S. Gould; J. Mills


Publisher
Springer
Year
1986
Tongue
English
Weight
817 KB
Volume
31
Category
Article
ISSN
0031-6970

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After i.m. injection nicomorphine is relatively slowly absorbed from the muscular depot and is found in the serum for approximately 1 h. The rate of absorption differs between patients and governs the overall pharmacokinetic profile of the compound. The relative AUCs were nicomorphine 18%, 6-nicotin