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Pharmacokinetics and its relation to toxicity of pegylated-liposomal doxorubicin in chinese patients with breast tumours

โœ Scribed by L. Xu; W. Wang; Y. C. Sheng; Q. S. Zheng


Book ID
108849326
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
266 KB
Volume
35
Category
Article
ISSN
0269-4727

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## BACKGROUND. Compared with free drug, sterically stabilized liposomal drug has prolonged circulation time and, thereby, higher tumor selectivity and antitumor activity. The stability in plasma is an important consideration in the formulation of clinically useful liposomal drug. A Phase I study o