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A dose escalation and pharmacokinetic study of biweekly pegylated liposomal doxorubicin, paclitaxel and gemcitabine in patients with advanced solid tumours

✍ Scribed by Bozionelou, V; Vamvakas, L; Pappas, P; Agelaki, S; Androulakis, N; Kalykaki, A; Nikolaidou, M; Kentepozidis, N; Giassas, S; Marselos, M

Book ID
109999191
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
113 KB
Volume
97
Category
Article
ISSN
0007-0920

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Phase I study of pegylated liposomal dox
Phase I study of pegylated liposomal doxorubicin and gemcitabine in patients with advanced malignancies
✍ Paula M. Fracasso; Kristie A. Blum; Benjamin R. Tan; Carole L. Fears; Nancy L. B πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 71 KB πŸ‘ 2 views

## Abstract ## BACKGROUND Pegylated liposomal doxorubicin (PEG‐LD) and gemcitabine have single‐agent activity in breast and ovarian carcinoma patients. We conducted a Phase I trial to evaluate the maximum tolerated dose (MTD) and toxicities of this combination in patients with advanced malignancie