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Dose escalation and pharmacokinetic study of irinotecan in combination with paclitaxel in patients with advanced cancer

✍ Scribed by John R. Murren; Kathleen Peccerillo; Susan A. DiStasio; Xin Li; Janine J. Leffert; Giuseppe Pizzorno; Barbara A. Burtness; Anne McKeon; Yung chi Cheng

Publisher
Springer
Year
2000
Tongue
English
Weight
119 KB
Volume
46
Category
Article
ISSN
0344-5704

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✍ Keith T. Flaherty; James P. Stevenson; Maryann Gallagher; Bruce Giantonio; Kenne πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 76 KB πŸ‘ 2 views

## Abstract ## BACKGROUND The authors performed a dose escalation study of cisplatin and the novel deoxycytidine analog, tezacitabine, to determine the maximum tolerated dose of the combination. ## METHODS Twenty‐three patients with advanced cancer and good performance status were accrued to 3 d