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Peptide variants reveal how antibodies recognize major histocompatibility complex class I

✍ Scribed by K. A. Hogquist; A. G. Grandea III; M. J. Bevan


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
864 KB
Volume
23
Category
Article
ISSN
0014-2980

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Major histocompatibility complex class I (MHC-I) molecules sample peptides from the intracellular environment and present them to cytotoxic T cells (CTL). To establish a selection system, and, thereby, enable a library approach to identify the specificities involved (that of the MHC-I for peptides a