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A viral peptide can mimic an endogenous peptide for allorecognition of a major histocompatibility complex class I product

✍ Scribed by Annick Guimezanes; Ton N. M. Schumacher; Hidde L. Ploegh; Anne-Marie Schmitt-Verhulst


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
387 KB
Volume
22
Category
Article
ISSN
0014-2980

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Cell-surface class I major histocompatibility complex (MHC) molecules present processed self-and nonself-peptides to thymus-derived (T) lymphocytes, allowing the intracellular compartment of cells to be sampled in order to detect infection. Since the class I MHC-peptide complex plays a critical role